are cookie paths necessary in multisite?

Getting ‘modify header’ errors using Remove Email Verification led me to lines 861-863 in pluggable.php which are all about cookies.

I then discovered that I have three lines related to cookies in my wp-config but I can’t remember why they were placed there. Are these required for any WPMU multisite plugins?

define('ADMIN_COOKIE_PATH', '/');
define('COOKIEPATH', '');
define('SITECOOKIEPATH', '');