sitewide activation not working in plugins

I am running multidata base, not sure if that would have anything to do with it or not, but I can’t seem to get the site wide activation for the plugins to work in mu 7.2.1

is there something I am missing I need to do to get this to work?

or maybe,,, when I activate sitewide plugins it will then only work on any new signups? and not currently active blogs?

Thanks for any help.

Tony V